St. Luke’s University Health Network uses Microsoft’s Security Copilot in Microsoft Defender as the central layer that connects its entire security stack. Instead of working in separate tools for alerts, access controls, and vulnerabilities, their team now relies on Security Copilot as the “connective tissue” that brings all of this data together.

In practice, that means Security Copilot:

• Aggregates alerts from across their environment into a single, AI-assisted view.
• Correlates access control events with potential threats.
• Surfaces vulnerabilities in context, so analysts can see what matters most.

This AI-powered, agentic approach helps St. Luke’s reimagine how their security team works, moving from manual, tool-by-tool investigation to a more guided, consolidated workflow.

St. Luke’s reports a clear, measurable benefit from using Security Copilot: they save nearly 200 hours every month in their security operations.

Those time savings come from:

• Reducing manual investigation across multiple tools.
• Speeding up triage and response by using a consolidated, AI-guided view.
• Automating parts of analysis that previously required repetitive human effort.

By reclaiming close to 200 hours per month, the security team can focus more on higher-value work such as proactive threat hunting, improving policies, and strengthening overall security posture.

At St. Luke’s, Security Copilot in Microsoft Defender acts as an AI-powered layer on top of their existing Microsoft security tools, including Microsoft Defender and Microsoft Sentinel.

In this setup:

• Microsoft Defender provides endpoint and threat protection signals.
• Microsoft Sentinel aggregates and analyzes security data across the organization.
• Security Copilot connects these signals and insights, giving analysts a consolidated, AI-driven view of alerts, access controls, and vulnerabilities.

This combination helps St. Luke’s reshape how their security operations center works—moving from fragmented data across tools to a more integrated, AI-assisted experience that supports faster, more informed decisions.